The plot centers around a group of friends who are traveling through the remote backwoods of West Virginia. Their journey takes a dangerous turn when they become stranded after a car accident. As they attempt to find help, they encounter a family of deformed, cannibalistic mountain dwellers who view the group as prey. The friends must use their wits and resourcefulness to survive against the relentless and gruesome threats posed by the local inhabitants.

“Wrong Turn” is noted for its tension-filled sequences, gory violence, and its portrayal of the hostile environment in which the characters find themselves. The film has garnered a following for its blend of horror and suspense, and it led to several sequels and a reboot, cementing its place in the horror genre.