Picking up after the events of Underworld: Blood Wars (2016), Selene (Kate Beckinsale) finds herself a fugitive, pursued relentlessly by both the vampire coven and the Lycans. In a desperate bid for survival, she joins forces with trusted allies like David (Theo James) and the fierce Nyssa (India Eisley). Together, they embark on a perilous quest to not only escape their enemies but to bring a decisive end to the age-old war between vampires and Lycans, facing dark new threats and uncovering long-buried secrets that could forever alter the fate of both species.